VIVA KAMBO! Kambo is the secretion extracted from the Phyllomedusa bicolor also known as the giant waxy tree frog found in the Amazon basin. Created by the most advanced pharmacist herself, Pachamama. Kambo’s unique cocktail of ‘ingredients’ contains bioactive peptides that enter through the lymphatic system and awaken the body’s self-healing abilities at a cellular level, and produce amazing benefits for the body and mind.

Kambo is one of the strongest natural anti-inflammatory, antibiotic, antimicrobial, and anesthetic substances found in the world, and one of the strongest natural ways to strengthen the immune system. Immediate and short-term effects include enhanced mood, alertness, clarity, focus, energy, and increased resistance to stress, tiredness, and anxiety. In the longer term, Kambo empowers the immune system, rousing the body’s natural defense systems to improve or resolve health problems.

Outside of the forest, Kambo has been the subject of three decades of medical research. What has been learned since is that the benefits of Kambo steam from the bioactive peptides and neuropeptides found in the Kambo secretion. Peptides are a fundamental part of nature, found in animals and humans alike. They are comprised of amino acids which are the build blocks of life – just like proteins are. Kambo introduces peptides into the body and literally introduces your body to the fountain of youth while waking up the body’s natural ability to heal itself on a cellular level.

So far, researchers have discovered dozen-plus peptides in Kambo, of which 16 are bio-active peptides are isolated. This means that each of these bioactive peptides has a direct connection to binding with receptor sites in the human brain. A receptor is like a lock that, when opened with the right key—the bioactive peptide—triggers specific chemical reactions in the body. There is even a peptide in Kambo that can provide pain relief up to 40x stronger than morphine!

The difference between a peptide from a protein is the number of amino acids that bond together. In short and how it works is the peptides are chemical signalers that serve as a bridge from the brain plasma membrane to the body and carry chemical messages to the body with specific instructions to do things.

When Kambo is administered to the body, the cell receptors freely open themselves up to the beneficial properties/peptides in Kambo. Since the peptides are just short chain amino acids, which are the building blocks of a protein, the cell receptors recognize these peptides as allies there to help and open up to the Kambo to allow it to come in and do its work. Kambo has the ability, unlike many other natural and pharmaceutical substances, to cross the blood-brain barrier and produce its effects also at the level of the brain. Unlike many substances that are filtered and eliminated by the body’s highly intelligent defense system. This unique ability enables it to reach much deeper into the body.

Peptides are essentially chemical signaling agents that use neurons to communicate with each other that serve as a bridge from the brain plasma membrane to the body and carry chemical instructions and messages to the body with specific instructions to do things. Bio-active peptides talk to the cell and give it instruction, they are cell enhancers.

Depending on the amino acids involved, peptides perform different biological functions in the body. Some perform hormone-like tasks, and others provide support for vital cellular processes (learning, memory, metabolism of certain neurotransmitters), providing support to cellular processes and functions within the body.

There are others that have a potent effect on the gastrointestinal muscle, gastric and pancreatic secretions, blood circulation, and stimulation of the adrenal cortex and pituitary gland and reproductive system, others possess potent pain-relieving powers.

Others have a potent effect on the gastrointestinal muscle, gastric and pancreatic secretions, blood circulation, and stimulation of the adrenal cortex and pituitary gland and reproductive system, others possess potent pain-relieving powers.

Kambo introduces peptides into the body and literally introduces your body to the fountain of youth while waking up the body’s natural ability to heal itself on a cellular level. WOW!

Traditionally Kambo has been used in these ways:

To cleanse, strengthen and energize the mind and bodies of the hunter while providing them with greater sensory perception, clarity, and increased stamina prior to hunting.

As a remedy for malaria, fevers, infections, and snake bites.

For treating “panema”– a word covering a range of negative situations and emotions such as sadness, bad luck, irritation, and dark or negative energies.

The ultimate goal of a Kambo ceremony is to achieve ‘healing’ and ‘cleansing’ of body, emotions, and spirit.

Presently, Kambo has gained recognition for providing short-term and long-term physical and psychological ailments. This natural remedy works its way throughout your system to flush what is no longer in service to your highest health and potential, clearing and aligning physical and energetic disturbances, and restoring balance. Individuals seek Kambo to find physical, emotional, and spiritual relief, while others use it to optimize their body.

Bio-active peptides found in Kambo have aroused a great deal of scientific interest. But so far, none of these molecules have been used in clinical practice. It is not to say that pharmaceutical companies have tried to produce the Kambo cocktail in their laboratories but have not been successful. Now it is up to us, above our rational and scientific culture, and accompanied and supported by it, to take advantage of this gift of nature and obtain all its benefits beyond what can be demonstrated by the multitude of pharmacological experiments carried out in scientific laboratories. The main families of bioactive peptides identified in Kambo secretion include:

Dermorphin and deltorphin – Have the potential to provide pain relief up to 4000x more potent than morphine!

These are small peptides composed of 7 amino acids. They are selective agonists of the opiate delta receptors, 4000 times more potent than morphine and 40 times more than endogenous endorphins.

Phyllomedusin – Increases secretion of the entire gastrointestinal tracts, and is responsible for the deep purge produced by Kambo.

A vasodilator and has a strong effect on the tear ducts, salivary glands, intestines, and bowels. Also known to produce contraction at the smooth muscle level and increases secretion of the entire gastrointestinal tracts such as the salivary glands, stomach, small and large intestines, pancreas, and gallbladder.

Phyllokinin and Phyllomedusins – Increases the permeability of the blood-brain barrier and reduces blood pressure.

Produces a long-lasting reduction in blood pressure. It helps widen the blood vessels and is responsible for the increased heart rate. They are potent vasodilators that increase the permeability of the blood-brain barrier both for their own access as well as for that of other active peptides. Within this family are the medusins, which also have antimicrobial and antifungal properties.

Caeruleins and Sauvagines – Improves digestion and has pain relief properties, and stimulates the pituitary gland and the adrenal cortex contributing to greater sensory perception and increased resistance and stamina.

These peptides with chains of 40 amino acids with myotropic properties on the smooth muscles, producing a contraction of the colon and urinary bladder. They produce a drop in blood pressure accompanied by tachycardia. They stimulate the adrenal cortex and pituitary gland, contributing to greater sensory perception and increased resistance. Both peptides possess a great analgesic power, contributing to the increase of physical strength, the capacity to confront physical pain, stress, disease and diminish symptoms of fatigue.

Adenoregulins (B2) –
Antimicrobial peptides that exhibit lethal effects against a broad spectrum of bacteria, fungi, yeast, and protozoa. The effects these antimicrobial peptides are having on the human brain are opening treatments for depression, stroke, and cognitive loss diseases such as Alzheimer’s and Parkinson’s disease.

Adenoregulins, discovered in the 90s by John Daly’s team at the National Institute of Health in the United States. Adenoregulin works on the human body through the adenosine receptors, a fundamental component throughout all human cellular fuel.

Dermaseptin – This neuropeptide is known for targetting bacteria, yeast, candida, and parasites.

Dermaseptin including adenoregulins (with 33 amino acids), platicins, and philloseptins form part of a family of a broad spectrum of antimicrobial peptides involved in the defense of frogs’ bare skin against microbial invasion. These are the first vertebrate peptides that show lethal effect against filamentous fungi responsible for severe opportunistic infections which accompany immunodeficiency syndrome. They also show lethal effects against a spectrum of bacteria both large, fungi, yeast, and protozoa (a group of single-celled eukaryotes, either free-living or parasitic). A neuropeptide that has also been found to inhibit the growth of yeast, candida, Albican, Staphylococcus aureus, and E. Colli.

Research carried out at the University of Paris has shown that peptides Dermaseptin B2 and B3 are effective in killing certain types of cancer cells. Research at Queens University in Belfast won a prestigious award for his ground-breaking work with cancer and Kambo. Its action mechanism is produced by inhibiting the angiogenesis of tumor cells, with selective cytotoxicity for these cells – targeting and looking for specific ill cells, unlike chemo. recently discovered this peptide promising results in anti-tumor and angiostatic properties.

Bradykinins – Produce vasodilation, increase vascular permeability.

Such as phyllokinins and tryptophilins. They are peptides with structure and properties similar to human bradykinin. They are important sources of scientific study as they are hypotensive and due to producing vasodilation, contraction of the non-vascular smooth muscle increased vascular permeability, also related to the mechanism of inflammatory pain.

Tryptophyllins – These peptides with an average length of 13 amino acids possess an action on liver protein synthesis and body weight, in addition, Tryptophyllins (TPH-7 and TPH-13) show endocrine and behavioural effects.

Bombesins – Stimulate the secretion of hydrochloric acid by acting on the G cells of the stomach. They also increase pancreatic secretion, intestinal myoelectric activity, and smooth muscle contractility.

Ceruleans – Stimulate the gastric, bile, and pancreatic secretions, and certain smooth muscles. They can be used in the paralytic ileus and as a diagnostic medium in pancreatic dysfunction.

What I feel pharmaceutical laboratories fail to take into consideration and underestimate and do not take into account/measure is the spirit and wisdom of the environment where the giant waxy tree frog of the Amazon inhabitants.

How long is the process?

From opening to close can be anywhere from 1-2 hours, with Kambo remaining on the skin for 20 minutes. It’s common that once Kambo is removed from the skin, one recalibrates almost instantly.

What Does It Feel Like When You Take Kambo?

Kambo is a relatively brief experience, lasting between 20-30 minutes, from the moment the Kambo is applied until it’s wiped off. Initially, superficial burns are made on the skin to remove the top layers. This is done to expose the lymphatic tissues, as this is how Kambo travels through the body. The rehydrated frog secretion is then applied to these burns, also known as gates. Shortly after the medicine is applied, you may experience a hard pounding heart, a flushed face, a feeling of pressure in your head, and a sensation similar to a niacin flush.

Nausea usually follows, with purging expected in 8 out of 10 cases. Purging can take many forms, including vomiting, using the restroom, shaking, sweating, emotional releases, or heavy mucus production.

After about 20-30 minutes, you’ll begin to feel much better and, after a period of rest, will be safe to drive home. We’ll explain the full range of symptoms in more detail in person so you know exactly what to expect and any fear of the unknown is dispelled.

Does it hurt?

The sensation will vary from person to person, depending on pain tolerance. There will be no blood and a small blister will form, which will be rubbed off gently. Each gate, or burn, will be done in less than a second with the ember of an herbal incense or stick. Each part of the body will feel different when burned. Most people describe the sensation as a slight pinch that passes quickly

Will I have scars?

Sometimes skin heals quickly and the burns will no longer be visible after a few months, other times it takes much longer depending on how well you heal and your skin type and complexion. Most people find they enjoy the markings and wear the scars as a badge of honor.

Are there any side effects?

The short answer is no. The experience after receiving Kambo is entirely dependent upon the individual. Most report feeling refreshed and rejuvenated. One thing to consider is what is known as the Herheimer reaction. This simply means that sometimes one will feel worse before feeling better as things move through your system.

What causes the purge?

Vomiting is believed to be controlled by two distinct brain centres–the vomiting centre and the chemoreceptor trigger zone. The vomiting centre initiates and controls the act of emesis, which involves a series of contractions of smooth muscles lining the digestive tract. There are server peptides in Kambo that stimulate the contraction of these smooth muscles. The chemoreceptor trigger zone is stimulated by many toxins and drugs. Activation of this brain region stimulates the vomiting centre, which initiates emesis in an effort to rid the body of the toxin. A good example of this is when you excessively ingest too much alcohol.

Does everyone purge?

No. In fact, a purge isn’t necessary to receive all the benefits for Kambo.

Will I be able to drive home after?

Yes, after adequate rest (20-45 minutes) you can drive home. It’s recommended to have some time for rest and integration after many, though many of my clients go to work the next morning. However, it’s recommended to allow time after a session with no scheduled obligations or commitments, at least for the rest of the day, to allow time for integration and rest.

What do I do post-ceremony?

Eating healthy, easily digestible foods, spending time in nature, and journaling is beneficial post-Kambo.

Are the frogs harmed in the process?

No, we personally know the people we receive Kambo from. The frogs are handled with extreme care and return the frogs back to the jungle safely after the secretion is extracted.

What is sananga eye drops?

Sanaga is a plant-based eye drops brewed from the Tabernaemontana genus of shrubs native to the upper Amazon basin. Click here to read more on Sanaga.

Still, have a question?

Contact Me!

• Curious about the Science of Kambo?

• Kambo and its Multitude of Biological Effects: Adverse Events or Pharmacological Effects?

• Antitumor and Angiostatic Activities of the Antimicrobial Peptide Dermaseptin B2

• Investigating the healing power of Kambo

• Active peptides in the skins of two hundred and thirty American amphibian species

• The Role of Adenosine Receptors in Psychostimulant Addiction

• Phylloseptin A Novel Broad-Spectrum Antimicrobial Peptide

• PsT-1: a new tryptophyllin peptide from the skin secretion of the Waxy Monkey Leaf Frog, Phyllomedusa sauvagei

• Deltorphins, A new class of potent opioid peptides from amphibian skin

• Dermorphin-related peptides from the skin of Phyllomedusa bicolor

• Frog secretions and hunting magic in the upper Amazon

• Sauvagine, a new polypeptide from Phyllomedusa sauvagei skin

• A Guide to Increasing Fertility

• Kambo and its Multitude of Biological Effects